An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities, Published online: 30 July 2018; doi:10.1038/nbt.4199

The precision of base editing is enhanced with an engineered version of the APOBEC3A deaminase.

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