Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice

Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice

Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice, Published online: 13 August 2018; doi:10.1038/nbt.4219

Diseases caused by different mutations in the two alleles of a gene are treated in mice by Cas-9-induced allelic exchange.

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